Hi Marisa,

I hope you had a good Easter. I am sending you a list of a few contributions that would be very valuable for the proposal. This is not an exhaustive list, I may ask you for more in the coming days, but at least you have something to start with:

Equity by design and behavioural phenotyping. This was a very good suggestion of yours and I would like to include a couple of paragraphs (maximum half page) in the methodology section. It is important that we explain very clearly how we are going to do this. If the plan is to do behavioural phenotyping of all young people who participate in the interventions, feasibility is paramount, so we need to keep it simple. We will be collecting some baseline data on young people participating in interventions, so we can collect some additional information, but we need to be mindful of capacity, resource requirements, and risk of young people dropping out if the protocol is too demanding. It would be ideal if we were able to gauge information for the behavioural phenotyping from direct observations, but I realise that this may not be possible.
Ideas for the digital literacy programmes (for each of the two intervention packages). We may have to involve some specialists through a sub-contract, in the end, but we do need to set out our plans for this important component of the interventions. I know we have not done a huge amount on this, but if you have any ideas on tackling misinformation, targeted marketing and addictive features of digital media use, this would be sufficient, in my view, to provide a plan on the scope of this component of the intervention. There will need to be a more basic version, for younger children in their mid-teen years, and a more advanced version for young people in their late teens and beyond.
Environmental nudges. I think we are reasonably well covered for environmental nudges in school environments, but we need options for the age group 19-25, especially if we are going to recruit them at the end of secondary school and follow them up in subsequent years in the different environments in which they will end up. This would make it difficult to change physical environments for a meaningful number of subjects. So, either we test environmental nudges separately, in environments that are relevant for young people in that age group (universities, workplaces), or we focus on giving young people the tools to better navigate their environments, whatever they are (e.g. food information apps).

Thank you.

Franco

From: Miraldo, Marisa <m.miraldo@imperial.ac.uk>
Sent: 03 April 2026 21:23
To: Sassi, Franco <f.sassi@imperial.ac.uk>; Olney, Jack J <jack.olney@imperial.ac.uk>
Subject: Z Health

Hi Franco and Jack apologies i had to leave earlier on the last meeting. Is there anything i can do to support the proposal?

Let me know how I can help.

All the best

Marisa

Marisa Miraldo, PhD

Co-Director, School of Convergence Science for Health & Technology

Professor in Health Economics

Department of Economics & Public Policy

Imperial College London, Business School
South Kensington Campus, London SW7 2AZ, UK

T: +44 (0)20 7594 9764

https://www.imperial.ac.uk/people/m.miraldo

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