FYI From: Dunsby, Christopher W Sent: 30 May 2017 16:47 To: Bruckbauer, Andreas <a.bruckbauer@imperial.ac.uk> Subject: Seminar by Alex Rohrbach Dear Andreas, The Photonics seminar this week by Alex Rohrbach on light sheet microscopy and optical tweezers may be of interest to some FILM users. Please could you advertise this via the FILM mailing list? best regards, Chris Professor Alexander Rohrbach http://www.imtek.de/professuren/bnp/startseite_bio-und_nanophotonik Thursday 1st June 4-5pm Huxley room 711c Novel photonics to observe biophysics on the small and fast scale Many new, exciting imaging techniques have emerged during the last decade, providing significantly improved spatial resolution and contrast. However, this extra information comes at the cost of more photons required to illuminate the target, which requires more time and energy and often damages biological structures. The smaller the structures to be investigated, the faster they usually move inside living cells, because of both Brownian motion and coordinated work of molecular motors. Can scattered laser light be a solution to the problem? In addition, a large fraction of fluorescence photons is scattered too often inside large objects and therefore diffusive photons do not reach the right pixels on the camera. A separation of diffusive photons would be helpful. In this talk I will demonstrate how nanometer scale displacements and motions of cellular structures and artificial probes can be observed by coherent optics, giving novel insights into principles of molecular mechanics of living systems. In addition, I will take a second look with you at the spreading of diffusive photons and how to separate their negative influence on image quality.