...forwarded for your information, Martin "Phenotyping TILs in situ: The enumeration and quantitation of phenotypic subsets of immune cells in tissue sections" *From:*SelectScience [mailto:product-news@selectscience.net] *Subject:* Webinar: Optical and microCT Imaging of Bacteria, Viruses and Tumors Your latest product and application news from _SelectScience_ <http://www.selectscience.net/>. You are subscribed to this service, if this email is no longer relevant please update your communication preferences _here_ <http://www.selectscience.net/SSUserAcc.aspx?mailID=5426&email=amcalcagno@bioline.com>. You can also read this as a _web version_ <http://www.selectscience.net/commNWDetails.aspx?mailID=5426&email=amcalcagno@bioline.com>. Webinar Ivis Imaging Attend our Live Webinar * *Optical and microCT Imaging of Bacteria, Viruses, and Tumors ** Examples of temporal and spatial analyses of various luminescent and fluorescent reporters /in vivo, ex vivo/ and /in vitro/ will be described. Tuesday, October 8, 2013 | 10 am Pacific | 1 pm Eastern | 6 pm GMT Register Now <http://www.selectscience.net/go/?itemID=7941&itemTypeID=4&linkID=imgctaregister&mailID=5426&email=amcalcagno@bioline.com&URL=https%3A%2F%2Fperkinelmerevents.webex.com%2Fperkinelmerevents%2Fonstage%2Fg.php%3Ft%3Da%26d%3D669647085%26utm_campaign%3DLST-WC-Q3-13-OPTIMAGINGTANGNEY-GLO%26utm_source%3DSelectScience%26utm_medium%3DEmail> The key to cancer therapy utilizing microbes is the ability to track the spread and replication of the bacteria or viruses within the body over time. A number of strategies employing IVIS^® optical imaging for tracking reporter constructs in different models, from /in vitro/ through to clinical samples have been developed. For bacterial work, novel /lux/ reporter constructs for luminescence imaging of different genera /in vitro/ and /in vivo/ in mice have been generated. This has permitted 2D and 3D whole body imaging for a wide range of both invasive and non-invasive species in different anatomical settings– in tumors, various deep organs, and even within the gastrointestinal tract of live animals. For eukaryotic work (tumors or viruses), luciferase tagged constructs permit similar imaging, the ability to monitor different luminescent reporters simultaneously (e.g. lux + Fluc within the same tumor), providing highly detailed monitoring of infections and host responses has been demonstrated. Additionally, techniques for luminescence imaging of microbes and gene delivery in patient tissue /ex vivo/ to provide clinically relevant data have been developed. Presented by: *Mark Tangney PhD. * Principal Investigator, Cork Cancer Research Centre, University College Cork, Ireland Mark Register Now <http://www.selectscience.net/go/?itemID=7941&itemTypeID=4&linkID=txtctaregister&mailID=5426&email=amcalcagno@bioline.com&URL=https%3A%2F%2Fperkinelmerevents.webex.com%2Fperkinelmerevents%2Fonstage%2Fg.php%3Ft%3Da%26d%3D669647085%26utm_campaign%3DLST-WC-Q3-13-OPTIMAGINGTANGNEY-GLO%26utm_source%3DSelectScience%26utm_medium%3DEmail> Human Health | Environmental Health © 2013 PerkinElmer, Inc. All rights reserved. PerkinElmer® is a registered trademark of PerkinElmer, Inc. All other trademarks are property of their respective owners. PerkinElmer, Inc. | 940 Winter Street | Waltham, MA 02451 USA | www.perkinelmer.com <http://www.selectscience.net/go/?itemID=7941&itemTypeID=4&linkID=txtperkinelmerwebsite&mailID=5426&email=amcalcagno@bioline.com&URL=http%3A%2F%2Fwww.perkinelmer.com%2F> SelectScience Ltd <http://www.selectscience.net/> SelectScience – Queen’s Award Winners <http://www.selectscience.net/product-news/SelectScience/SelectScience-Celebrates-Queen%E2%80%99s-Award-for-Enterprise/?&artID=28438> Copyright 1998 - 2013 SelectScience Ltd. All rights reserved. Company Registration No. 3597730. Science House, Church Farm Business Park, Corston, Bath, BA2 9AP UK. Other offices in North America and Germany. *_See Career Opportunities

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