Department of
Medical Biochmistry and Biophysics
Division of
Vascular Biology
Postdoc
in
angiogenesis
focused on live cell and
in vivo
confocal
imaging
Department
The Department
of Medical Biochemistry and Biophysics conducts
multidisciplinary research and
education in
biomedicine. Presently our department consists of 11
research divisions with a total of
approximately
300 employees.
The Division of
Vascular Biology
provides an
international and
interactive
environment with
seven research
groups;
Christer
Betsholtz, Ulf Eriksson, Jonas Fuxe,
Johan
Björkegren, Lars Jakobsson, Guillem Genové and Daniel
Nyqvist.
Area of research
/ Research group
The research
group of D
r. Daniel
Nyqvist is investigating molecular mechanisms
regulating vascular
growth and
barrier function in health and disease. We study
angiogenesis during developmental
processes and in
pathophysiological conditions such as tumor growth and
retinopathy. W
e are a
young, dynamic
and very enthusiastic research team with a well
-
established
collaborative network
and strong
funding.
Please visit
the group website:
985&l=en
The project will
be focused on visualizing cellular processes
underlying vessel growth and function
using one
-
and two
-
photon laser
-
scanning
microscopy both
in vivo
and in live
cell cultures. The
work will take
advantage of established applications for intravital
imaging in the anterior chamber
of the eye (AC)
and
ex vivo
organ cultures,
but also include development of novel methods. A wide
range of
fluorescent repor
ter
s
and genetically
modified mou
se models will
be used to study
vessel
growth and
function, both in healthy conditions and in disease
state
s
such as tumor
angiogenesis.
Two new state
-
of
-
the
-
art confocal
imaging systems will be available for these studies.
Lab r
eferences:
Nyqvist et al., Diabetes 2011, Corada et al., Dev Cell
2010, Speier, Nyqvist et al.,
Nat Med 2008.
Qualifications
of the applicant
We are seeking a
highly motivated researcher with a good team spirit
and deep curiosity for
science. The
ideal
candidate
should have a strong background in one
-
and two
-
photon
microscopy,
image processing
and animal physiology with a keen interest in vascular
biology.
Experience in
working with
confocal microscopy is a must, and experience from
working with mice an
d molecular
biology
techniques is a strong plus; and good ability to
communicate in English (written and verbal)
is required.
Candidates will be encouraged to serve as mentors for
master
-
and
PhD
-
students.
Type of
scholarship
Karolinska
Institutet awards
scholarships to
pursue postdoctora
l studies.
This
educational
scholarship,
which is paid for a maximum of two years within five
years after the receipt of a PhD
or the
equivalent, is tax
-
exempt.
Application
process
An application
must contain the follow
ing documents
in English:
•
Personal letter
of motivation
•
Curriculum
vitae (max 3 pages)
•
Complete list
of publications
•
Summary of
current work (1 page)
•
Two reference
letter
s
•
Ph.D. degree
certificate or a formal document from the dis
sertation
-
committee
stating the
date of
dissertation
The application
is to be submitted on the NetRecruiter system
;
.
Starting date is
negotiable, but
beginning of
fall 2014 is preferred.
For
further
information
please email
to