Dear Colleagues, We are pleased to invite you to take part in the NIKON Imaging System Demo Week, which will run from Monday 24th to Friday 28th November (ICTEM Building; Room 304A). The system on demonstration is the NIKON ECLIPSE Ji Open Architecture Digital Inverted Microscope<https://www.microscope.healthcare.nikon.com/en_EU/products/digital-microscopes/eclipse-ji/research>. It is equipped with the CREST X-Light V3 Spinning Disk Confocal System<https://www.microscope.healthcare.nikon.com/en_EU/products/confocal-microscopes/crest-x-light-series/crest-x-light-v3>. The platform supports two main modes of use: 1. Automatic Assay Imaging<https://downloads.microscope.healthcare.nikon.com/phase7/literature/Brochures/ECLIPSE-Ji-Assay_2CE-MJTH-2-A.pdf> – minimal user interaction; AI-driven setup and analysis for high-throughput cellular imaging assays. 2. Advanced Research Mode<https://downloads.microscope.healthcare.nikon.com/phase7/literature/Brochures/ECLIPSE_Ji_Research_2CE-MJEK-1-A.pdf> – full access to JOBS visual programming<https://www.microscope.healthcare.nikon.com/en_EU/products/software/nis-elements/nis-elements-advanced-research> for customised image acquisition and analysis workflows. Our motivation for evaluating this system is to identify an instrument that can: * Support Master’s research projects efficiently and productively. * Provide high-sensitivity imaging with over 95% quantum yield for detecting biological processes under physiological conditions. * Integrate smoothly with modern AI and image analysis tools<https://www.microscope.healthcare.nikon.com/en_EU/products/software/nis-elements/nis-ai-1>. * Deliver high-speed imaging<https://crestoptics.com/x-light-v3-2/> of tissue and organoid samples. The FILM staff team is fully prepared to support the demo, with both David and myself experienced in maintaining and developing NIKON microscope platforms. For reference, I am also the first author of NIKON’s strategies combining automatic focus tracking with multi-point time-lapse imaging<https://github.com/vzloy/NIS-JOBS-GA3/blob/main/Nikon%20Practical%20Tips%201%20-%20Ti2%20PFS%20and%20WID-2.pdf> If you are interested in testing the system, please let us know so we can reserve a slot for you. We can also accommodate long-term overnight live-cell imaging upon request. The demo will be scientifically supported by Associate Professor Jorge Bernardino de la Serna<https://profiles.imperial.ac.uk/j.bernardino-de-la-serna> (NHLI). We look forward to your participation and feedback. Best regards, Volodymyr