following feedback from FILM users and Wellcome Trust grant
holders (see summary at the bottom), the FILM steering committee has
decided to use the open call for Wellcome Trust Multi-User Equipment
grant applications to apply for upgrades / updates of existing
equipment as well as some novel technology. The highest demand is
currently for a new super-resolution microscope, which is luckily
already funded by BBSRC, we are now in the process of testing the
equipment to be purchased. Other demands stretched across a wide
range of technologies and unfortunately also locations across the
college, the committee tried to strike the best balance between all
needs and decided to apply for the following package:
New technology:
an automated high-throughput microscopy
system (e.g. Operetta or similar)
the high-throughput capacity, in
combination with existing image processing / analysis capacity
(e.g. Definiens) will satisfy the needs for both the
high-content screening and to a large degree ImageStream needs
Upgrade:
upgrade
of the existing intravital microscope (FILM-CF3) with
options including high-sensitivity hybrid
detectors, 405 laser, a cabinet for mouse handling, laser
dispersion correction (detailed options to be checked with
manufacturers)
Support:
one full-time
FILM staff post for Hammersmith for the duration of the
grant
Replacement:
a
high-sensitivity new-generation confocal (similar to the
Zeiss LSM-780 in
Hammersmith), to be located in SAFB / South Kensington
Possible options for
small, complementary equipment add-ons:
FleXcell
Tensions System
ONIX
microfluidic platform (if not
already funded by other sources through other sources)
a
high-precision multi-channel peristaltic pump
system
Obviously, we can't apply for everything on the list at the same
time, some things will have to wait for the next equipment grant
call.
We now need to finalise the application - and for that we need
your support: Those of you willing to support the application
with your scientific interest and track record, please do get back
to us soon - the deadline for the preliminary application is 2nd of
December.
And although the major bits of equipment to go on the application
have been decided, if there are smaller add-ons missing on the list
that would help with your microscopy in FILM, please let us know.