Dear All

As some of you may be aware, before he left, Martin applied for funds for a High Content Screening unit.   

This has been successful and we are now at the stage of testing available models

If anyone has an application for this type of instrument  or samples they would like tested or be involved in the testing then please contact us.

The following was in the original application:

High-content screening (HCS) microscope with confocal modality

Required specifications will include:

· Brightfield and phase contrast imaging,

· 5 excitation lasers for multi-parameter imaging,

· Multi-channel confocal or multi-camera acquisition for high speed,

· Upgrade option for temperature incubation.

Projects:

· Assays for phenotyping

· RNAi screens aimed at dissecting actin binding proteins and Rho GTPase signalling important for stable epithelial cell-cell contacts and polarity, with impact on epithelial homeostasis and diseases. 

· Acquisition of high quality images in large scale

· Invasion assays

Bw

Steve

FILM - Facility for Imaging by Light Microscopy

**************************************************************
Steve Rothery
FILM Technician
Sir Alexander Fleming Building, desk 403
Imperial College London / South Kensington
Exhibition Road
London SW7 2AZ
Tel +44-(0)207 594 9793

And

ICTEM, (L-Block) Room 314
Hammersmith Campus
Imperial College London
Du Cane Road
London, W12 0NN
Tel. +44-(0)207 594 1669

E-mail  s.rothery@imperial.ac.uk
Website: http://imperial.ac.uk/imagingfacility
**************************************************************