March 2012 - FILM-Users - imperial.ac.uk

[FILM-Users 00178] Fwd: TODAY! Invitation to the inaugural lecture of Professor Ralph Knöll
by Martin Spitaler 21 Mar '12

21 Mar '12

...forwarded, for your information, Martin -------- Original Message -------- Subject: TODAY! Invitation to the inaugural lecture of Professor Ralph Knöll Date: Wed, 21 Mar 2012 09:16:24 +0000 From: Watson, Emma M <e.watson(a)imperial.ac.uk> To: Faculty of Medicine, NHLI <icsm-nhli-dl(a)imperial.ac.uk> The honour of your company is requested at an inaugural lecture: "Molecular mechanisms and future therapies in heart failure" Professor Ralph Knöll, Chair in Myocardial Genetics Date: Wednesday 21 March 2012 Time: 17.30 – 18.30 Venue: Lecture Theatre G16, Sir Alexander Fleming Building, South Kensington Campus (building no 33 on the map). Travel information for the South Kensington Campus can be found on the Imperial website. A pre-lecture tea will take place from 16.45 in the Foyer, Sir Alexander Fleming Building. RSVP: Emma Watson e.watson(a)imperial.ac.uk Cardiovascular diseases such as heart failure are the most common cause of death globally. Although major advances have been achieved during the last decades, our understanding of the underlying molecular mechanisms, necessary to develop new therapeutic strategies, remains incomplete. One such mechanism is mechanosensation, the fundamental process by which cells sense mechanical stimuli and convert them into biomechanical signals. Mechanosensation is also linked to mechanoptosis, a recently described type of cell death only found after an increase in biomechanical stress in striated muscles such as the heart. A diverse group of diseases has now been linked to mutations in the Z-disc proteins that form the segments separating the sarcomeres – the smallest functional units of striated muscle. These Z-discopathies can lead to perturbations in mechanosensation and apoptosis. Developing ways of combating cardiac myocyte cell death is key to finding ways to combat these lethal conditions. Professor Knöll was recruited to Imperial as a Professor and Chair in Myocardial Genetics in October 2009 from the Georg August University, Göttingen, Germany, where he was a Professor as well as Head of the Working Group in Cardiovascular Molecular Genetics since 2004. He was a Postgraduate Researcher and then Group Leader at the Institute of Molecular Medicine, UC San Diego, from 1999 to 2004. He did his clinical training at the Charité in Berlin and his professional training at the Max-Planck-Institute of Physiological and Clinical Research, Department of Experimental Cardiology, and was educated at Johann Wolfgang Goethe University Medical School, Frankfurt and Justus Liebig University Medical School, Giessen. Professor Knöll is a referee for a number of prominent journals, including Circulation, Molecular and Cellular Biochemistry, European Journal of Heart Failure, and Clinical Cardiology. He is a Member of the European Society of Cardiology, the American Heart Association, and the German Cardiac Society, and has won numerous awards including the Theodor Frerichs Award from the German Society for Internal Medicine and the Fritz Acker Award from the German Cardiac Society.

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[FILM-Users 00177] FW: Register for the Correlative Microscopy Webinar
by Martin Spitaler 21 Mar '12

21 Mar '12

...forwarded, for your information, Martin *From:*Cell Press [mailto:cellpress@mail.cell-press.com] *Sent:* 20 March 2012 19:40 *Subject:* Register for the Correlative Microscopy Webinar Cell Press Register for a Free Webinar ------------------------------------- Correlative Microscopy ------------------------------------- Live date: Wednesday, April 4, 2012 12:00 Noon US ET -------------------------------------Register Today, It's Free... Hear about the latest applications of correlative microscopy from Dr. John Briggs, Dr. Mark Ellisman, Dr. Carolyn Larabell, and Dr. Peijun Zhang during this exciting webinar from Cell Press. Light microscopy has been providing information on the location of key molecules that can be tracked by staining or fusion to fluorescent proteins at ever increasing resolution, while electron microscopy has traditionally been used to provide high resolution views of the overall ultrastructure of samples. New approaches and equipment are now allowing more scientists to combine these two techniques to provide a unified view of the location of biological molecules in the context of the full structure of a sample, and these are collectively referred to as correlative microscopy. Register Today, It's Free...: <http://mediazone.brighttalk.com/event/ReedElsevier/6de59d960d-5973-intro> Unable to join us on April 4? This webinar will be archived for 6 months for on-demand viewing. Register today to ensure you receive updates on how to gain access after the live event! Be sure to check out our archive of past webinars at http://www.cell.com/webinars Moderated by: Paul Wiseman, Associate Professor of Physics and Chemistry, McGill University Speakers: Carolyn LarabellCarolyn Larabell National Center for X-ray Microscopy John BriggsJohn Briggs Cell Biology and Biophysics Unit, European Molecular Biology Laboratory Peijun ZhangPeijun Zhang Department of Structural Biology, University of Pittsburgh Mark EllismanMark Ellisman National Center for Microscopy and Imaging Research Supporting Journal: Biophysical Journal Cell Press

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[FILM-Users 00176] food in microscope rooms
by Martin Spitaler 20 Mar '12

20 Mar '12

Dear microscopists, it seems it's necessary again to remind everybody that eating and drinking is NOT allowed in any FILM microscope room! Recently it happened more often again that coffee cups and coke cans appeared in the rooms. All our microscopes are lab space, and harmful chemicals (fixatives, nuclear stainings, oncogene transfections, ...) are regularly used in sample preparation. As in any lab, traces of them will accumulate on the microscopes, computer keyboards etc. There is a real reason for the rule; plus, it can get us into serious troubles with the health and safety inspectors. This should also remind you of obvious lab behaviour, that it's a good idea to wash your hands after leaving the rooms, and that it's not a good idea to bite your nails either, no matter how exciting (or frustrating) the experiment. Thanks for your cooperation, good imaging, Martin -- ------------------------------------------------------------------------ *Martin Spitaler, PhD* *FILM - Facility for Imaging by Light Microscopy* - Facility Manager - Sir Alexander Fleming Building, desk 401 Imperial College London / South Kensington Exhibition Road London SW7 2AZ UK Tel. +44-(0)20-759-42023 E-mail m.spitaler(a)imperial.ac.uk <mailto:m.spitaler@imperial.ac.uk> Website: http://imperial.ac.uk/imagingfacility

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[FILM-Users 00175] webinar on super-resolution
by Martin Spitaler 08 Mar '12

08 Mar '12

...forwarded, for your information, Martin WEBINAR: BioTechniques / Leica Microsystems: "Beyond the Diffraction Limit: Advances and Applications of Super-Resolution Imaging" Wednesday, March 28, 2012 1 PM ET / 10 AM PT / 5 PM GMT https://event.on24.com/eventRegistration/EventLobbyServlet?target=registrat… -- ------------------------------------------------------------------------ *Martin Spitaler, PhD* *FILM - Facility for Imaging by Light Microscopy* - Facility Manager - Sir Alexander Fleming Building, desk 401 Imperial College London / South Kensington Exhibition Road London SW7 2AZ UK Tel. +44-(0)20-759-42023 E-mail m.spitaler(a)imperial.ac.uk <mailto:m.spitaler@imperial.ac.uk> Website: http://imperial.ac.uk/imagingfacility

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