News Release CONTACT: Corbin Collins MDL Information Systems, Inc. (510) 895-1313, ext. 1371 corbin@mdli.com http://www.mdli.com European mirror site: http://www.mdli.co.uk SPRING ACS: MDL UNITES INDUSTRY-LEADING SCIENTIFIC SOFTWARE WITH WORLD'S LARGEST ORGANIC CHEMISTRY DATABASE --The ISIS Beilstein Interface Provides Familiar ISIS Access to Beilstein's Structure, Reaction, and Data Repository-- SAN LEANDRO, California--March 22, 1999--MDL Information Systems, Inc. now offers scientists who appreciate the flexible, intuitive capabilities of the industry-leading Integrated Scientific Information System (ISIS) the same ISIS access to the Beilstein Database. The ISIS Beilstein Interface enables researchers to use most ISIS search options--as well as Beilstein-specific capabilities--to query and retrieve chemical structures and data from the world's most comprehensive source in organic chemistry. Anyone familiar with ISIS for searching MDL or proprietary databases can use the application without significant retraining. For companies with existing ISIS/Host installations, the ISIS Beilstein Interface is easy to install and administer. The ISIS system communicates with the database via a new gateway based on the protocols of CrossFire 4.0, Beilstein's native search engine. MDL will demonstrate the ISIS Beilstein Interface at the meeting of the American Chemical Society, March 22-24, booth 819, Anaheim Convention Center. "I'm very pleased with the introduction of this product," said Dr. Alexander Lawson, director of research and development, Beilstein Informationssysteme GmbH (BIS). "The ISIS Beilstein Interface significantly extends the capabilities of one of the world's most comprehensive chemistry databases, enhancing the value of ISIS and Beilstein alike." "The ISIS Beilstein Interface is an example of the kind the synergy we expect to achieve with BIS and other subsidiaries of our parent company, Elsevier Science," said Patricia Rougeau, president and chief executive officer of MDL. "With the ISIS Beilstein Interface, many MDL customers who appreciate ISIS' power, flexibility, and ease-of-use can take full advantage of the enormous Beilstein resource." Options for Remote Access The ISIS Beilstein Interface supports most ISIS queries-molecule searches, reaction searches, text and property searches, combined substructure and data searches-and several Beilstein-specific capabilities. Users can conduct searches across a corporate client/server network or via the Internet. Corporate access on an in-house system requires that organizations store all server components of the ISIS Beilstein Interface on a corporate server or servers (the CrossFire search engine and Beilstein database can be installed on one server, the ISIS Beilstein Gateway on another). For Internet access, companies simply install the ISIS Beilstein Gateway on a corporate server and subscribe to CrossFire Direct Service, which operates with a backup system to ensure reliability and which saves a company the work of installing and maintaining CrossFire and the Beilstein Database. About the Beilstein Database Beilstein's chronological index dates from 1771, and contains over 7.5 million compounds, 10 million reactions, and 30 million associated physical, chemical, and biological property records that can be accessed through 300 data fields, 250 keyword fields, and 80 numeric physical property fields. Beilstein contains three primary data types. The substance domain stores structural information, including chemical, physical, and biological properties, preparative methods, chemical behavior,and literature references. The reaction domain offers more details on the preparation of substances and reaction attributes such as reaction centers, bond fates, and atom-atom mapping. The citation domain contains citations, abstracts, and titles related to entries in the substance and reaction domains. About ISIS The ISIS family of products provides an information management architecture that supports the registration, management, retrieval, display, and analysis of all types of scientific information. ISIS/Host is the foundation server system. ISIS/Draw is a desktop chemical drawing program used to create chemical presentation graphics or compose database queries. ISIS/Base is a desktop database management system that provides the capability to store, search, and display chemical structures and associated data with customizable forms. About the Companies MDL Information Systems, Inc. is the recognized leader in discovery informatics for the life science and chemical industries. MDL software, content, and services provide the enterprise framework for identifying successful new products. A wholly owned subsidiary of Elsevier Science, MDL has offices worldwide with headquarters in San Leandro, California. Beilstein Informationssysteme GmbH, based in Frankfurt, Germany, and Beilstein Information Systems Inc., with offices in San Leandro, California, are the developers of the CrossFire System, the world's leading authority on organic chemical information, and AutoNom, a program for automatically generating IUPAC names from graphic structures. BIS is a wholly owned subsidiary of Elsevier Science. ### MDL is a registered trademark and ISIS is a trademark of MDL Information Systems, Inc. AutoNom, CrossFire, and CrossFire Direct are trademarks of Beilstein Informationssysteme GmbH. Beilstein Data by Beilstein Institut fuer Literatur der Organischen Chemie licensed to Beilstein Chemiedaten & Software GmbH and Beilstein Informationssysteme GmbH. Microsoft is a registered trademark of the Microsoft Corporation. All other product names may be trademarks or registered trademarks of their respective holders. Dori Luzbetak Web Communications Manager Marketing Communications MDL Information Systems, Inc. 14600 Catalina Street San Leandro, CA 94577 (510) 895-1313 x1652 (510) 614-3608 - FAX dori@mdli.com chemweb: A list for Chemical Applications of the Internet. To post to list: mailto:chemweb@ic.ac.uk Archived as: http://www.lists.ic.ac.uk/hypermail/chemweb/ To (un)subscribe, mailto:majordomo@ic.ac.uk the following message; (un)subscribe chemweb List coordinator, Henry Rzepa (mailto:rzepa@ic.ac.uk)