Chemical Information and Computation 2016 Number Two; 252nd ACS National Meeting and Exposition, Philadelphia, PA, August 21-25, 2016 We are pleased to announce the publication of our 48th report in this series. It starts with the usual news section covering people, awards, and industry news, and recent developments at over 60 organizations in the computational chemistry, cheminformatics, chemical information, and publishing markets. It also has detailed transcripts of technical presentations in ACS symposia on cheminformatics, sharing pharmaceutical industry data, and harnessing the literature to inform rational compound design, including topics such as free energy calculation, biological networks, data semantics, chemogenomics and other databases, and matched molecular pairs. A further five presentations from other meetings cover miscellaneous topics such as AI in drug discovery, patents, research funding, and a computational notebook. A report on the Herman Skolnik Award symposium (already available on open access) is appended. Order forms at http://www.warr.com<http://www.warr.com/>. Contents list at http://www.warr.com/morepubs.html. Fifty percent discount to academia and government. Wendy Dr. Wendy A. Warr Wendy Warr & Associates 6 Berwick Court, Holmes Chapel Cheshire, CW4 7HZ, England Tel./Fax +44 (0)1477 533837 wendy@warr.com<mailto:wendy@warr.com> http://orcid.org/0000-0002-7064-4739 http://www.warr.com<http://www.warr.com/> Skype: wendyannewarr Twitter: @WendyAnneWarr